Monday, July 26, 2010

Obesity and Obesity Prevention

OBESITY & ITS PREVENTION
       Obesity, most common problem relating to general health of the people now-a-days is however not looking so serious at primary stage, but it can be the reason for diseases such as heart disease, diabetes, arthritis and some cancers. Here we are going to introduce obesity, its major risk factors, how unintentional weight gain occurs and preventive steps which should be taken. Achieving healthy weight can help you control your cholesterol, blood pressure and blood sugar thus help you to prevent weight-related diseases.
        If you are overweight, you are not alone. 66% of adults in the U.S. are overweight or obese. While, almost 40% of all americans are overweight. Also, in india above 9 crore people are suffering from obesity.
        Unintentional weight gain occurs when a person takes in more calories than the body needs or uses. As we age, our metabolism slows, which can cause weight gain unless we also reduce the amount of food we eat and get adequate exercise. Weight gain can also be a significant symptom of several endocrine diseases. A rapid weight gain may be a sign of dangerous fluid retention.
Causes of weight gain:
Alcohol use
Certain drugs such as Corticosteroids, Cyproheptadine, Lithium, Tranquilizers Phenothiazines etc.
Cushing syndrome
Eating too much and exercising too little
Emotional factors such as guilt, depression, and anxiety
High-carbohydrate, high-calorie diet
Hypothyroidism
Polycystic ovary syndrome
Slower metabolism, which is normal with aging
Quitting smoking
       Besides this, Foods high in fat can lead to unwanted weight gain. Consuming too much saturated and trans fats may increase LDL cholesterol level and increase your risk of heart disease.
Preventive steps you should take:
       To maintain your weight, the calories you eat must equal the energy you burn. To lose weight, you must use more calories than you eat. A weight-control strategy includes.

Choosing low-fat, low-calorie foods
Eating smaller portions
Drinking water instead of sugary drinks
Being physically active
Product profile:
Simlim Capsule(Weight Control Therapy)
● Vasu’s Simlim is researched herbal product, which can be safely used for weight loss because it has no side effects.
Simlim is composed of finest Indian herbs known for their positive role in fat etabolism, helps to reduce body weight. However, it maintains nutritional balance. It is an herbal supplement to help reduce excess body weight.
Composition :
Each capsule contains extract derived from
Garcinia combogia (Vrukshamla / Kokam)  : 1200 m
Bauhinia variegata (Kanchanar) : 800 mg
Clerodendron phlomides(Agnimantha) : 600 mg
Terminalia chebula(Haritaki) : 400 mg
Commiphora mukul(Guggulu) : 250 mg
Allium sativum(Lasuna) : 150 mg
Picrorrhiza kurrooa(Katuki) : 80 mg
Excipients : q.s.
Indications: Obesity, Reduction in excess fat, Reduction in excessive craving for food or sugar and maintain normal shape of body.
Dosage: 2 capsule twice a day, fifteen minutes after breakfast and dinner. After achieving the desired weight loss, reduce capsule intake to 1 capsule twice a day. For best results continue treatment with Simlim at least for 3 months. To be effective, Simlim should be taken along with a reduced calorie diet and 20 minutes to 1 hour of moderate physical activity
Pharmacological Action of Principal ingredient:
       Garcinia, an internationally acclaimed herb prevents conversion of excess carbohydrates into fats. Guggulu is reported to reduce cholesterol and triglycerides. Haritaki is digestive and helps reduce absorption of excess fat from intestine.
       One of the major ingredient of simlim capsule is Garcinia combogia which is claimed to give following activities:
1. Anti-obesity and anti-adipogenic activity :
       It is found that that Garcinia cambogia-derived (-)-hydroxycitric acid (HCA) is a safe, natural supplement for weight management. HCA is a competitive inhibitor of ATP citrate lyase, a key enzyme which facilitates the synthesis of fatty acids, cholesterol and triglycerides. Garcinia extract also inhibits the cytoplasmic lipid accumulation as well as adipogenic differentiation of preadipocytes. Further human studies have been warranted.1
2. Hypolipidemic activity :
       It has also been examined that an administration of Flavonoids from Garcinia cambogia, significantly lowered lipid levels in rats, fed normal and cholesterol containing diets. β-Hydroxy β-methyl glutaryl coenzyme A reductase showed significant reduction in normocholesterolemic rats.2
References:
1. 1. Preuss, HG., Rao, CV., Garis, R., Bramble, JD., Ohia, SE., Bagchi, M., Bagchi, D., 2004. An overview of the safety and efficacy of a novel, natural (-) hydroxycitric acid extract (HCA-SX) for weight management. Journal of Medicine. 35(1-6), 33-48.


2. 2. Asha Sarah Koshy, L. Anila, N.R. Vijayalakshmi, 2001. Flavonoids from Garcinia cambogia lower lipid levels in hypercholesterolemic rats. Food Chemistry 72, 289-294.

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